Probably you will have noticed some people (men), that they go out with women in a club, cafe etc. This is not bad, but many people are afraid to approach a woman (or a group), with a man in this group.
Most of them are just “orbiters” and are men that are friends, colleagues or brothers with these girls. I recommend to you the first thing to do is to watch if the girl touches or kisses any man of this group, before you approach this girl.
In one group i approached, after i watched the people there, the man was gay and a friend of my target.
So, don’t hesitate to approach a mixed group, but do it only if you are sure about their relationship.